Is Caffeine Bad For Liver

Is Coffee Bad For Your Liver The Answer May Shock You

With an increased interest in coffee over the last few years, there have been multiple studies conducted to assess the negative and positive effects of coffee on the body.

As such an essential part of your body, it is important to take care of your liver. The question is, does drinking coffee help you do that or does it only work to damage your liver?

How Cocaine Causes Liver Damage

Is cocaine bad for your liver? A lot of research has focused on how cocaine affects the heart, since heart attack is the leading cause of death for people who abuse cocaine. And when we hear about drug use and liver damage, we assume its about alcohol because liver disease is linked to alcoholism.

Cocaine is also extremely harmful to the brain and spinal cord thanks to dopamine and norepinephrine.

But while stories like these get much of the spotlight, cocaine is working behind the scenes, steadily and aggressively attacking your liver. Each time you consume cocaine, youre flooding your body with more and more toxins that your liver cant filter out. Not only does this constant cocaine use increase your chances of suffering an overdose, it also harms your liver.

Studies have shown that long-term cocaine use can impair its ability to function and can result in spikes in liver enzyme levels.

Other effects cocaine has on the liver include:

• Viral hepatitis
• Arterial hypotension
• Rhabdomyolysis (the release of dead muscle fibers into the bloodstream

Furthermore, agents are often added to cocaine to cut it in order for it to increase its weight. Drug dealers will often use chemicals such as fentanyl, amphetamines, caffeine, laundry detergent, laxatives, and boric acid to increase their margins. These agents serve to increase the toxicity of the cocaine to your liver.

Caffeinated And Decaffeinated Coffee

Four studies reported RRs of HCC specifically for decaffeinated coffee consumption. No single study reported a statistically significant association between HCC and decaffeinated coffee consumption. Three cohort studies, involving approximately 750000 participants and 800 cases, reported doseresponse RRs or RRs for > 2consumption categories. The pooled RR of HCC for two extra cups per day was 0.86 . Only two studies, involving approximately 850000 participants and 900 cases, reported RRs of HCC according to caffeinated coffee consumption in a manner suitable for doseresponse analysis. The pooled RR of HCC for an extra two cups of caffeinated coffee was 0.73 .

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Can Caffeine Cause Liver Damage

Most of the time, caffeine actually appears to be protective against liver damage, particularly the damage caused by alcohol or hepatitis C, says San Francisco-based James Wantuck, MD, an internal medicine physician and chief medical officer and cofounder of the telehealth platform PlushCare.

A February 2017 study in the European Journal of Gastroenterology & Hepatology linked drinking coffee regularly with a lower risk for non-alcoholic fatty liver disease , a condition affecting millions, and for liver scarring among those who had NAFLD. Other research found a lower risk of progression to liver cirrhosis, or severe scarring of the liver, among people with chronic liver disease who drank coffee daily, according to an April 2014 study in Liver International.

For the average adult, up to 400 milligrams of caffeine appears to be safe, per UM. The average cup of brewed coffee has 96 milligrams of caffeine, according to the USDA. Bottom line, drinking up to four cups of coffee a day shouldn’t cause issues. Because energy drinks can have many times the amount of caffeine as a cup of coffee, according to the Center for Science in the Public Interest, read labels carefully. One a day could be your limit.

For Liver Health Black Coffee Is Golden

Black coffee is ideal for liver health, Wakim-Fleming advised, as dressing up coffee with cream or sugar pours on added fat and stress for the liver to process. The Cleveland Clinic added: “If you just can’t stomach it black, swap sugar for artificial sweeteners. Add skim milk or plant-based milk instead of cream.”

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Drink Coffee Not Tea To Ward Off Liver Cirrhosis

A new study has found that drinking coffee may significantly reduce ones risk of death from liver cirrhosis, specifically non-viral hepatitis-related cirrhosis.

There is no good treatment option for chronic liver disease, especially if unrelated to chronic viral hepatitis, said senior author Woon-Puay Koh, PhD, Associate Professor, Office of Clinical Sciences, Duke-NUS Graduate Medical School Singapore, and Saw Swee Hock School of Public Health, National University of Singapore, Singapore. Hence, there is a need to identify potential therapeutic agents that may retard the disease process. Since coffee is widely consumed globally, it thus has significant clinical and public health implications.________________________________________________________________________________________________________________________________________________________________________

Drinking Coffee Can Benefit Long-Term Memory________________________________________________________________________________________________________________________________________________________________________

The researchers did not detect a link between the consumption of tea, fruit juices, or soft drinks and the risk of death from cirrhosis.

Researchers also reported that coffee consumption was not linked to viral hepatitis B-related cirrhosis mortality.

After an average follow-up of nearly 15 years, nearly 15,000 deaths were reported, including 114 deaths from liver cirrhosis.

Reference

Drink Up: Large Study Confirms Coffee Beneficial To Liver Health

Oct. 26, 2021 — Drinking more than three cups of caffeinated coffee a day is associated with fewer liver problems, according to a new study.

The study is likely the most rigorous look to date on the benefits of coffee on liver health in the U.S. It was based on data from the National Health and Nutrition Examination Survey which asked people about what they eat and drink.

âThis is the closest weâre ever going to get to a linkage between what people are eating or drinking and the health of their liver, absent a longitudinal study where we set out to follow people for many, many years,â said Elliot Tapper, MD, assistant professor of gastroenterology at the University of Michigan, and the studyâs senior author.

Researchers looked at data from about 4,500 patients who had participated in the survey in 2017-2018. The participants were 20 years old or older, with an average age of 48 73% were overweight, about the national average.

The researchers found no connection between coffee consumption and a measure of fatty liver. But they found a link between coffee and liver stiffness.

Those who drank more than three cups of coffee daily had a lower liver stiffness measure measured in whatâs known as kilopascals. Liver stiffness higher than 9.5 kilopascals is a sign of liver fibrosis, which can lead to cirrhosis.

Tapper said the data will be reassuring to doctors who suggest coffee-drinking to patients.

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Caffeinated Drinks May Be Good For The Liver

Researchers have discovered that an increased caffeine intake may reduce the risk of non-alcoholic fatty liver disease, according to a study published in the journal Hepatology.

A team from the Duke-NUS Graduate Medical School and the Duke University School of Medicine used cell culture and mice as models for the effects of caffeine on the liver disease.

The study found that consuming the caffeine equivalent of four cups of coffee or tea a day may prevent and protect against the progression of non-alcoholic fatty liver disease in humans.

People with NAFLD have a build up of extra fat in liver cells that is not caused by alcohol according to the American Liver Foundation, up to a quarter of Americans have the disease, and there is no treatment, only prevention through diet and exercise.

The studys researchers show that caffeine reduces fat content within the liver and stimulates -oxidation in hepatic cells and liver via an autophagy-lysosomal pathway.

Paul Yen, associate professor at Duke NUS, says:

This is the first detailed study of the mechanism for caffeine action on lipids in liver and the results are very interesting.

Coffee and tea are so commonly consumed and the notion that they may be therapeutic, especially since they have a reputation for being bad for health, is especially enlightening.

Other research has suggested that consuming around two cups of coffee a day could be linked to urinary incontinence in men.

About Coffee And Liver Health

This study adds to the growing evidence that coffee benefits the liver, according to Dr. Albert Do, a Yale Medicine hepatologist, clinical director of the fatty liver disease program, and associate professor at Yale University.

There are previous studies suggesting lower risk of cirrhosis , improvements in fatty liver disease, lower rates of hospitalization and mortality in cirrhosis, associated with coffee use, Do said.

Many studies have shown that coffee consumption is linked to lower liver enzyme levels.

Much of the time, high levels of liver enzymes arent a cause for concern, but they can be a sign of inflammation or damage in the liver.

Another extensive review from 2016 found that drinking coffee may help offset liver damage associated from overconsuming certain foods and alcohol.

According to Dr. Tamar Taddei, a Yale Medicine hepatologist and associate professor at Yale School of Medicine, its difficult to pinpoint how and why coffee may combat liver disease.

It may have anti-inflammatory or anti-fibrotic properties, the two main and interrelated pathways to liver disease and liver cancer, Taddei said.

There may also be other contributing factors at play that havent yet been identified.

More research is needed to explore how coffee along with the ways in which its made may improve the health outcomes in people with liver problems.

People who develop heartburn or gastrointestinal issues should adjust their intake depending on what they can tolerate.

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Is It Bad To Have An Energy Drink Everyday

daydrink energy drinksday

Thereof, what are the effects of energy drinks on the body?

Potential risks associated with energy drink consumption include:

• caffeine overdose
• type 2 diabetes as high consumption of caffeine reduces insulin sensitivity.

How long do energy drinks last in your system?

45 minutes4 to 6 hoursabout 4 to 6 hours

How long do the effects of an energy drink last?

five hoursabout two hours

How To Have A Healthy Liver

Drinking coffee is just one way to keep your liver healthy. Dr. Wakim-Fleming says its also important to get vaccinated against hepatitis A and hepatitis B viruses, which both damage the liver.

A healthy diet is also key. The liver is the first organ to metabolize the foods we eat. Eating a lot of high-sugar, high saturated-fat foods can lead to fatty liver disease, she says. And of course, heavy alcohol drinking can permanently damage the liver and lead to cirrhosis.

However, coffee isnt a miracle worker. It wont completely reverse liver disease or undo the damage caused by excessive alcohol use. But it can be one delicious and satisfying step toward a happier liver.

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So How Much Coffee Should You Consume To Reap All Of The Benefits While Avoiding The Bad Side Effects

Most women can consume three to five cups of coffee per day, with a maximum caffeine intake of 400 mg, according to the Dietary Guidelines for Americans. The restrictions are different if you’re pregnant or breastfeeding. Before including caffeine in your diet, consult your obstetrician.

You want to do things that make you happy. Even if you only drink one cup of coffee each day, or even decaffeinated coffee, you can reap some of the possible health benefits. Also, keep in mind that the ingredients you use in your coffee can affect how healthy it is. Instead of cream and sugar, Vizthum recommends using up to two tablespoons of milk, milk replacement, or half-and-half, as well as naturally sweet spices and flavourings. For added flavour, toss in a 14 teaspoon of the following:

• Extract of vanilla
• Cocoa powder Cardamom Cinnamon
• Eating a well-balanced diet, exercising regularly, and keeping a healthy weight are some of the aspects that have a significant impact on your health. Coffee should only be used as a supplement to these important health considerations.

Coffee Helps Your Liver Enzymes

This is true for coffee, decaf coffee, and energy drinks which use coffee as a base. “Coffee consumption is associated with improvement in liver enzymes, especially in individuals at risk for liver disease. Coffee intake more than 2 cups per day in patients with preexisting liver disease has been shown to be associated with lower incidence of fibrosis and cirrhosis, lower hepatocellular carcinoma rates, as well as decreased mortality.”

This episode was requested by YouTube username Legendary 27huNdREd54.

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What Else Is In Your Drink

The caffeine isn’t the only think that could hurt your liver. Look at the whole picture, the “food matrix”. For example:Did you know an excess of Vitamin B3 can cause liver damage? Try to avoid drinks with more than 100% DV niacin. And ask questions if you aren’t familiar with the other ingredients in your drink.

Coffee And An Association With Decreased Liver Enzymes

In numerous studies, it has been noted that coffee consumption has been associated with decreased levels of aspartate aminotransferase , alanine aminotransferase , gamma-glutamyltransferase , and alkaline phosphatase . One of the first studies to document consumption of coffee with relatively decreased GGT was in 1985 in the Tromsø Heart Study. That same year, another study noted an inverse relationship between coffee consumption and AST and ALT levels amongst both Korean and Japanese immigrants. These studies began an investigation into elucidating a more direct relationship between coffee and possible hepatoprotective properties. The Tromsø study looked at multiple beverages, notably including green tea. Since 1985 multiple other studies have been performed with similar findings when testing specifically for the possible effect of coffee consumption on liver disease.

While studies had been performed previously testing for coffee consumption and its association with liver enzyme levels, one study evaluated effect of coffee in patients with risk factors for chronic liver disease: consumption of greater than two alcoholic beverages daily, positive serum HBV antigen, positive serum HCV antibody, transferrin saturation > 50%, elevated BMI, and uncontrolled diabetics. This study demonstrated relatively reduced levels of ALT amongst these higher risk groups.

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Case 1 Acute Liver Injury Attributed To Use Of Energy Drinks

A 22 year old woman developed low grade fever, abdominal pain, nausea and vomiting and was found to have abnormal liver tests having been consuming 10 cans of energy drinks daily for 2 weeks. On examination in the emergency room, she had epigastric tenderness but no other findings and was sent home. The following day she developed jaundice and was seen again and admitted to the hospital. She denied alcohol or drug abuse and was not taking other medications. Laboratory tests showed marked elevations in and but normal levels of bilirubin, alkaline phosphatase and . The INR was 1.6. Acetaminophen levels were undetectable. There was no serologic evidence of acute hepatis A, B, C or E and tests for Epstein Barr virus and cytomegalovirus infection were negative. She was managed conservatively. She did not undergo liver biopsy or imaging studies. Serum aminotransferase levels decreased rapidly and she was discharged four days later. In follow up one month later, she was asymptomatic and serum ALT levels were normal.

Key Points

Coffee And Risk Of Other Liver Diseases

Coffee drinking has also been related to a reduced risk of other liver diseases. A systematic review published in 2014 suggested coffee consumption was associated with beneficial outcomes in patients with chronic liver disease, cirrhosis, hepatocellular cancer and NAFLD6. A 2016 review also concluded that coffee intake of more than 2 cups per day in patients with pre-existing liver disease was associated with a lower incidence of fibrosis and cirrhosis, lower hepatocellular carcinoma rates, and decreased mortality8.

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Coffee And Likely Protective Effects Against Development Of Fibrosis

Coffee clearly correlates with reduced frequency of fibrosis, but is coffee itself responsible for these effects, or can its probable protection against fibrosis be seen utilizing any caffeinated beverage? Other studies referenced above seem to suggest hepatoprotection is unique to coffee amongst caffeinated beverages, however, a 2001 study attempted to answer this question head-on. This group noted that caffeine intake from other beverages did not show significant odds ratio along with no evidence of significant trends over the amount of intake whereas with coffee intake there was an inverse association with cirrhosis and coffee consumption with just one cup of coffee daily. A 2012 study found a similar association of reduced observation of advanced in coffee drinkers but not in espresso.

There is always a concern when findings of a beverage are correlated with health benefits that there may be confounding factors in play. In a case-control study performed in Italy, it was confirmed that the inverse relationship between coffee consumption and cirrhosis across strata of tobacco use, alcohol consumption, age, and sex. A consistent inverse relationship was still noted in moderate alcohol drinking indicating the relationship between coffee consumption and cirrhosis is not restricted to alcohol-related cirrhosis.

Is Decaffeinated Coffee Good For Your Liver

There are several arguments about the benefits of decaf coffee. For many years, people have believed that all the benefits of coffee are due to its caffeine. Recently, however, all that changes.

Some researchers for the US national institute of cancer published a study that suggests that drinking coffee generally decaf or not, is good for the liver. This suggests that there is something in coffee that offers benefits to the liver other than its caffeine.

The rate of coffee consumption in Europe and the United States is high. According to the US National Coffee Association, more than half the population of adults in the US takes an average of three cups of coffee daily in 2010.

According to the association, the value has been on the rise by a yearly increase of 1% every year since the 1980s.

Studies in the past showed that coffee could have positive protective effects on the liver. Also, these studies show that drinking coffee can reduce the risks of people developing cardiovascular disease, diabetes, non-alcoholic fatty liver disease, cirrhosis and liver cancer.

However, with the evidence available from the past, one cannot say if all the benefits apply to decaffeinated coffee as well.

According to the lead researcher, Dr Qian Xiao from the National Cancer Institute, “prior research found that drinking coffee may protect the liver. However, the evidence did not clearly state if the benefit extends to decaffeinated coffee.”

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