Does Caffeine Cause Breast Cancer

June 4, 2022

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Preparation Methods Of Coffee And Tea Are Also Contradictory

Does Caffeine Cause Breast Cancer?

Not only do results on the effect of coffee on breast cancer risk vary with age, menopausal status, and more, but the method by which it’s prepared adds another variable. A 2019 study on Chinese women in Hong Kong found that consuming coffee products did not increase the risk of breast cancer.

When broken down by preparation methods, however, there were significant differences. Women who drank brewed coffee, for instance, were, on average, 52%less likely to develop breast cancer. In contrast, those who drank instant coffee were 50% more likely to develop the disease.

Just as proper preparation of green tea is essential to obtain the phytonutrients present, the way coffee is prepared could easily affect the nutrients present.

There are many factors at play when it comes to the relationship between coffee and breast cancer. Hormone therapy and other risk factors play a far stronger role on the risk of breast cancer than coffee does.

Effect On Absorption Of Folate Or Other Nutrients

Alcohol might affect the bodys ability to absorb some nutrients, such as folate. Folate is a vitamin that cells in the body need to stay healthy. Absorption of nutrients can be even worse in heavy drinkers, who often consume low levels of folate to begin with. Low folate levels may play a role in the risk of some cancers, such as breast and colorectal cancer.

Breasts Genes And Coffee

Drinking three cups of coffee a day shrinks womens breasts, the Daily Mail reported. It said that researchers had questioned nearly 300 women on how much coffee they drank, and then measured the size of their bust. The study found that three cups was enough to make breasts shrink, with the effect increasing with each cup. The newspaper said there is a clear link between drinking coffee and smaller breasts, as about half of all women possess a gene that links breast size with coffee intake.

Previous research has found that risk of breast cancer may be affected by a particular oestrogen balance in the body, a balance that seems to be associated with breast volume. This is influenced by a gene that codes for an enzyme involved with both oestrogen and caffeine metabolism. The current study looked at whether coffee intake is associated with breast volume, and how this is modified by which variant of the gene CYP1A2*1F a woman carries. Although it did find a link between these factors in women who did not use oral contraception, the media has over-simplified the results, and the study has few implications at the current time. The study only looked at these factors at one point in time, and cannot demonstrate that coffee consumption caused the tested breast volume, or causes breasts to shrink.

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Coffee Cuts Risk Of Liver Cancer

Research has found that regular coffee consumption can reduce the risk of liver cancer by 40 percent. In fact, the studypublished in Clinical Gastroenterology and Hepatologyfound that people who consume more than three cups of coffee per day reduce their risk by more than 50 percent.

Researchers conducted a meta-analysis of data collected between 1996 and 2012 and then selected 16 studies that involved a total of 3,153 liver cancer cases. They included data on 900 more recent cases of HCC published since their last detailed study from 2007.

They found that individuals who consume any amount of coffee have a 40 percent reduced risk of HCC compared to those who drink no coffee. Whats more, the higher the consumption, the more the risk was reduced. Those who drank more than three cups per day had a 50 percent or more reduced risk. The association between coffee and reduced risk was consistent regardless of gender, alcohol consumption, or history of hepatitis or liver disease.

The researchers concluded that coffee appears to reduce the risk of liver cancer. They speculate that it might affect liver enzymes and the development of cirrhosis and therefore, could protect against liver cancer.

Why Is This Study Important

Does Caffeine Cause or Reduce the Risk of Breast Cancer?

Many people regularly drink coffee and tea. This study finds that these beverages are not harmful and may be linked to a lower risk of death after a breast cancer diagnosis. For breast cancer survivors who are concerned with how diet affects their chance of cancer returning, this study adds some clarity to one part of daily life.

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Good Genes Are Nice But Joy Is Better

In a large group of patients with metastatic colorectal cancer, consumption of a few cups of coffee a day was associated with longer survival and a lower risk of the cancer worsening, researchers at Harvard-affiliated Dana-Farber Cancer Institute and other organizations report in a new study.

The findings, based on data from a large observational study nested in a clinical trial, are in line with earlier studies showing a connection between regular coffee consumption and improved outcomes in patients with non-metastatic colorectal cancer. The study is being published today by JAMA Oncology.

The investigators found that in 1,171 patients treated for metastatic colorectal cancer, those who reported drinking two to three cups of coffee a day were likely to live longer overall, and had a longer time before their disease worsened, than those who didnt drink coffee. Participants who drank larger amounts of coffee more than four cups a day had an even greater benefit in these measures. The benefits held for both caffeinated and decaffeinated coffee.

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Can Caffeine Treat Breast Cancer Along With Traditional Therapy

Caffeine has antioxidant and anti-inflammatory functions. Antioxidants counteract oxidationa chemical process that leads to cancer and heart disease. Inflammation worsens disease, including cancer. For these reasons, caffeine has been considered as a possible treatment for breast cancer when combined with traditional therapies.

A 2020 study showed that that caffeine combined with chemotherapy drug, cisplatin, is an effective treatment for breast cancer by shifting the energy metabolism of two known triple-negative breast cancer lines, and significantly increasing the efficacy of cisplatin to treat the cancerous cells. Triple negative breast cancer is highly aggressive due to the absence of hormone receptors.

A laboratory experiment evaluated the response of cancer cells to caffeine. The researchers found that cell growth was suppressed in estrogen receptor-positive and estrogen receptor-negative samples.

They also noted that women who consumed high amounts of caffeine and were treated with tamoxifen for breast cancer prevention were less likely to develop the condition. The researchers theorized that caffeine can make women more sensitive to the beneficial effects of the drug.

Because findings in laboratory experiments are not always the same when they are applied to humans, the effects of caffeine on breast cancer cells would have to be replicated in humans in a clinical trial before it would be accepted as a treatment for breast cancer.

Can Caffeine Affect Breast Cancer Outcomes

Can coffee cause breast cancer?

A 2021 study suggests coffee may improve breast cancer survival, according to the American Institute for Cancer Research. People drinking more than three cups of coffee a day had a 25% lower risk of dying from breast cancer compared with those who abstained from coffee.

People drinking three cups of tea daily after a breast cancer diagnosis had a 26% lower risk of dying from any cause compared with people who did not drink tea.

Other factors included breast cancer treatment, body mass index , and physical activity.

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Is Caffeine Really Bad For You A Doctor Weighs In

What you should know before you down your next cup of coffee.

Donât dump out your coffee quite yet.

Mmmm, coffee. If youâre anything like me, you canât live without a morning cup . But with all the fear mongering about how caffeine might give you heart disease or cancer, you may be feeling a little freaked out about the habit.

I was mainly terrified at the prospect of having to quit coffee, so I did some research and talked to Dr. Matthew Chow, a neurologist and assistant clinical professor at UC Davis, to get the lowdown on caffeine intake. He told me everything you need to know, including who should stay away from the stuff, what health benefits it could provide and how to know when you need to quit.

Are There Benefits To Drinking Coffee

Coffee has been associated with a variety of health benefits. In some of the studies weve discussed above, weve seen that coffee may actually lower the risk of some cancers. Here are some other possible benefits of drinking coffee:

According to the American Institute for Cancer Research, coffee is a good source of riboflavin as well as other antioxidants.
A 2015 study of three large cohorts found that coffee consumption was associated with a lower risk of total mortality as well as inversely associated with risk of death due to cardiovascular and neurological diseases.
A 2017 review of studies found that coffee consumption was associated with a lower risk of conditions such as type 2 diabetes, Parkinsons disease, and several liver diseases. The authors also found that coffee consumption was associated with a lower risk of death from all types of cardiovascular disease.
A 2018 study found that both caffeinated and decaffeinated coffee increased alertness compared to a placebo. This indicates that some of the behavioral benefits of coffee may extend beyond the effects of caffeine.

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Search Strategy And Study Selection

The publication search strategy, selection of eligible studies, data extraction, risk of bias assessment and Grading of Recommendations Assessment, Development and Evaluation were conducted by two independent researchers , and any controversies were resolved by discussion with an experienced reviewer . We searched PubMed, Embase and the Cochrane Library to identify potentially eligible studies published in the last 30 years up to April 2020 with original search terms of coffee or tea and the risk of BC and breast carcinoma but no language restrictions . Eligible studies evaluated coffee and/or tea consumption for the risk of incident BC with their MeSH terms. Manual searches using reference lists in similar publications of each potential studies were also conducted. Potential publications analysed the association of coffee or tea consumption with the risk of incident BC, compared doseresponse correlations or non-coffee and tea groups and were either casecontrol studies or prospective cohort studies.

What Interpretations Did The Researchers Draw From These Results

The authors conclude their main finding of a significant interaction between coffee consumption, CYP1A21F genotype and breast volume among young healthy women who did not use hormonal contraceptives. The researchers say that this interaction was mainly driven by the fact that coffee consumption of three cups a day or more was associated with lower breast volume in women who did not have the CYP1A21F A/A genotype.

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Caffeine And Fibrocystic Breasts

, chief of breast surgery at the Miami Cancer Institute, Baptist Health South Florida, tells Verywell that caffeine can be problematic in some cases. For example, even the small amount of caffeine that is found in chocolate may increase breast pain in premenopausal women who have fibrocystic breasts.

Fibrocystic breasts are a benign condition in which the breast tissue is dense and lumpy. In people with the condition who have yet to go through menopause, fibrocystic breasts can cause pain that may or may not be associated with their menstrual cycle. As they age, the denser breast tissue turns into softer fatty tissue, and the breast pain decreases.